Which test detects acetoacetate and acetone (to a lesser degree)?

Which test detects acetoacetate and acetone (to a lesser degree)?

• A. Nitroprusside test
• B. Keto-Diastix
• C. Acetest Tablets
• D. Clinitest

Answer: (C)

Ketone detection in urine relies on the nitroprusside reaction, which responds most strongly to acetoacetate and, to a lesser degree, to acetone. Acetest Tablets are a prepared form of this reaction used specifically to screen for ketones in urine. When acetoacetate is present, the reagent on the tablet changes color, and acetone can also trigger a weaker color change, allowing ketone presence to be detected even if acetone is the dominant ketone in some situations. Beta-hydroxybutyrate, another major ketone body, does not produce a strong signal with this reagent, which is why this test is particularly noted for acetoacetate (and acetone to a lesser extent). The other options either test for different substances or use formats that aren’t as targeted for detecting these ketone bodies.

Ketone detection in urine relies on the nitroprusside reaction, which responds most strongly to acetoacetate and, to a lesser degree, to acetone. Acetest Tablets are a prepared form of this reaction used specifically to screen for ketones in urine. When acetoacetate is present, the reagent on the tablet changes color, and acetone can also trigger a weaker color change, allowing ketone presence to be detected even if acetone is the dominant ketone in some situations. Beta-hydroxybutyrate, another major ketone body, does not produce a strong signal with this reagent, which is why this test is particularly noted for acetoacetate (and acetone to a lesser extent). The other options either test for different substances or use formats that aren’t as targeted for detecting these ketone bodies.